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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK6
All Species:
13.03
Human Site:
S207
Identified Species:
20.48
UniProt:
Q9NQU5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQU5
NP_001122100.1
681
74869
S207
Q
S
S
P
P
G
A
S
P
P
T
G
T
N
R
Chimpanzee
Pan troglodytes
XP_510301
627
67581
L186
E
T
D
R
E
R
L
L
P
G
R
V
K
G
S
Rhesus Macaque
Macaca mulatta
XP_001093484
681
74821
S207
Q
S
S
P
P
G
A
S
P
P
T
T
T
G
R
Dog
Lupus familis
XP_544614
968
105825
S494
Q
S
S
P
P
G
T
S
P
P
T
A
T
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULB5
682
74848
S208
Q
S
S
P
P
G
T
S
P
P
M
A
T
G
R
Rat
Rattus norvegicus
Q62829
544
60692
Q103
E
Q
W
A
R
L
L
Q
T
S
N
I
T
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515215
639
68748
P198
P
P
A
S
A
A
A
P
P
G
R
A
E
K
A
Chicken
Gallus gallus
XP_426393
667
74767
G207
Q
H
V
P
A
L
P
G
D
G
D
K
M
G
K
Frog
Xenopus laevis
NP_001082100
650
73749
D202
R
R
E
Y
P
G
N
D
R
G
H
S
D
P
V
Zebra Danio
Brachydanio rerio
XP_001919719
693
77347
P207
P
P
P
P
F
P
V
P
E
P
P
R
P
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
Q198
P
S
L
L
Y
N
S
Q
H
A
H
A
N
G
A
Honey Bee
Apis mellifera
XP_001122147
624
70155
L183
T
Q
N
M
I
P
N
L
Q
N
L
N
P
N
M
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
Q131
T
Q
G
E
S
S
G
Q
K
W
L
Q
Y
D
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
Y358
V
D
S
K
T
G
E
Y
T
G
L
P
E
E
W
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
T356
D
S
N
T
G
Q
F
T
G
L
P
K
E
W
Q
Conservation
Percent
Protein Identity:
100
52.7
98.5
66.4
N.A.
92.5
30.6
N.A.
62.2
75.9
46.7
52.5
N.A.
44.3
44.9
29.8
N.A.
Protein Similarity:
100
60.7
98.9
67.6
N.A.
95.5
48.4
N.A.
69.9
82.3
61.6
64.5
N.A.
57.5
57.5
47.2
N.A.
P-Site Identity:
100
6.6
86.6
80
N.A.
73.3
6.6
N.A.
13.3
13.3
13.3
13.3
N.A.
6.6
6.6
0
N.A.
P-Site Similarity:
100
20
86.6
86.6
N.A.
73.3
13.3
N.A.
20
20
20
13.3
N.A.
13.3
13.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
14
7
20
0
0
7
0
27
0
0
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
7
0
0
0
0
7
7
0
7
0
7
7
0
% D
% Glu:
14
0
7
7
7
0
7
0
7
0
0
0
20
7
0
% E
% Phe:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
7
40
7
7
7
34
0
7
0
34
0
% G
% His:
0
7
0
0
0
0
0
0
7
0
14
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% I
% Lys:
0
0
0
7
0
0
0
0
7
0
0
14
7
14
7
% K
% Leu:
0
0
7
7
0
14
14
14
0
7
20
0
0
7
7
% L
% Met:
0
0
0
7
0
0
0
0
0
0
7
0
7
0
14
% M
% Asn:
0
0
14
0
0
7
14
0
0
7
7
7
7
14
0
% N
% Pro:
20
14
7
40
34
14
7
14
40
34
14
7
14
7
0
% P
% Gln:
34
20
0
0
0
7
0
20
7
0
0
7
0
0
7
% Q
% Arg:
7
7
0
7
7
7
0
0
7
0
14
7
0
0
27
% R
% Ser:
0
40
34
7
7
7
7
27
0
7
0
7
0
7
7
% S
% Thr:
14
7
0
7
7
0
14
7
14
0
20
7
34
0
0
% T
% Val:
7
0
7
0
0
0
7
0
0
0
0
7
0
0
7
% V
% Trp:
0
0
7
0
0
0
0
0
0
7
0
0
0
7
7
% W
% Tyr:
0
0
0
7
7
0
0
7
0
0
0
0
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _